Switch of glycolysis to gluconeogenesis by dexamethasone
gluconeogenesis Gluconeogenesis ADP + Pi GTP COO– C O Pyruvate carboxylase CH2 Phosphoenolpyruvate Oxaloacetate carboxykinase COO–Figure Reversal of the reaction of Pathway · Gluconeogenesis is a pathway consisting of eleven enzyme-catalyzed reactions · Gluconeogenesis begins with the formation of oxaloacetate through
The problem for Gluconeogenesis was that the enzymes hexokinase and PFK were irreversible Gluconeogenesis occurs in the liver and kidneys The gluconeogenesis pathway helps maintain blood glucose levels during fasting or low
Pathway · Gluconeogenesis is a pathway consisting of eleven enzyme-catalyzed reactions · Gluconeogenesis begins with the formation of oxaloacetate through Gluconeogenesis Gluconeogenesis is essentially a reversal of glycolysis, and the primary substrates for gluconeogenesis are pyruvate, lactate